Alloreactive natural killer cell therapy for multiple myeloma

Abstract. Disease relapse is an important problem after allogeneic stem cell transplantations in multiple myeloma (MM). To test the.







BMT CTN Protocol 0201, URD PB vs BM - ClinicalTrials.gov
The PhD thesis studies the mechanisms of regulation of the activation of Natural Killer cells, focusing on their anti-tumor activity.
Le Fc?RIIIA/CD16A des cellules Natural Killer (NK) humaines
Membrane expression of the killer immunoglobulin-like receptor (KIR) KIR2DL4 on peripheral blood NK (pNK) cells is controlled by the 9A/10A ...
Caractérisation de l'hétérogénéité tumorale et du compartiment ...
sequence homology suggests that KIR genes are quences are apparently alleles at a single locus (Gardi- likely to be regulated by a stochastic mechanism, possi-.
Distinct KIR/HLA compound genotypes affect the kinetics of ... - JCI
The killer-cell immunoglobulin-like receptors (KIR) are type I transmembrane glycoproteins that are expressed on NK cells and subsets of T cells.
KIR gene complexity in primates - UU Research Portal
Specific NK-cell recognition of cells expressing the Bw4-positive HLA-B allo- types was demonstrated and shown to correlate with staining by the DX9 and Z27.
killer-ig-like-receptors-kirs-their-role-in-nk-cell ... - SciSpace
In the same years, NKB1 was described as a 70 kDa glycoprotein, whose expression was detected by. DX9 mAb, and DX9pos NK clones recognized a ...
Genetic Diversity and Structural Complexity of the Killer-Cell ...
The KIR gene complex is highly polymorphic, with genetic diversity, structural intricacy, and copy number variability, making genotyping ...
un nouveau défi thérapeutique pour le rejet d'organe i - HAL Thèses
Notre équipe a récemment démontré que l'incapacité des cellules endothéliales du greffon à transmettre des signaux inhibiteurs dépendant des molécules HLA-I ...
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