Bioisosterism: A Rational Approach in Drug Design

One of the first drugs used clinically was arsphe- namine (36, Figure 26). The activity of arsphe- namine against the syphilis organism was attributed to its ...







Reactions of 2,3-Dibromonaphthalene-1,4-Dione and ... - SciSpace
Abstract. In this work, the products formed by the reaction between 2,3-dibromonaphthalene-1,4-dione with. (pyridine-2-yl)methanamine and ...
Manganese and Nickel Complexes as Catalysts for Aromatic Oxidation
This introduction chapter aims at providing a general overview on aromatic oxidation reactions catalyzed by metalloenzymes as well as synthetic first-row ...
Cyclometallated platinum compounds: optical and biological ...
TD-DFT calculations were performed for compounds 8x and 9x and their precursors in solution, using the geometries previously optimized, to calculate the UV ...



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Design of an allosterically regulated retroaldolase