Transcriptional responses to DNA damage - IDEKER LAB
Exogenous DNA damage, on the other hand, occurs when environmental, physical and chemical agents damage the DNA. Examples include UV and ionizing radiation, ...
Replication Stress, DNA Damage, Inflammatory Cytokines ... - HALFormation of cytoplasmic inclusions (CIs) of TDP-43 and FUS, along with DNA damage accumulation, is a hallmark of affected motor neurons in ... Mechanisms of DNA damage, repair and mutagenesis - COREThese DNA lesions/adducts arise from a vari- ety of endogenous and exogenous sources, including chemical mutagens, UV radiation, reactive oxygen ... 1 DNA damage response defects induced by the formation of TDP ...Endogenous metabolites and exogenous agents such as UV light induce a variety of chemical alterations in the primary structure of DNA. These ...
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