13?2 ????????????????

?????????????????????????. ?????????????????????????. ??? ??????????????????????. ??? ...

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????????? Discussions on Sample Size - ?????

CONSORT???STROBE??????????. ????20????????? ... ???????????????. ????????????????????????.

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?? ????????????????????

T ?? p ????????. ????????????????0.05 ??. ?????????????????????. ?????? P ??0.05 ?????????.

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???????? - BioMarin Pharmaceutical Japan

?????? t ?. ?????p ??0.05 ??????????????????. 425. 2014 ? 11 ?. ?17?. ? 1 ??????????DD?????????. WISC?. AD ...

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?????????? - ??????

?1?Microsoft Excel???????????????????? ... PRA = 1 + TD * TD / (2 * df). PRA = Sqr(PRA). PR1 = PR1 / PRA. PR1 ...

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? ????????????????

??????k?5???3 ????H?50.9 ?C?0.5981 ????p?0.05. ??????????????????????????? PP ???? ...

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? ????????????????

??????k?5???3 ????H?50.9 ?C?0.5981 ????p?0.05. ??????????????????????????? PP ???? ...

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??????????????? ????? ????????? ...

... ?????2???????AChR???????3???. ?T????????4 ... ????????? ????????????????????????????.

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?????1 - College Analysis ???????

2????????????. ???????????? ? 10 pooled t ?????? ? 11 pooled Wilcoxon ?????? ... ???????????????????.

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????????????? ????????????

... t? ???. ?,P?0.05?. ? ??? ???. § ??. D?. ????????????????. ???????????????.QT?. ????. ?0.496±0.054sec?ACh ...

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2.00 ??????????? - PMDA

tD = t0.5 ? 0.5tG(?). 72. tM = ????????????????(20?) ... ??(??)???????????????????????. 452. ??????? ...

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(9) ??????????? - R??????? R???????

????????????? 0.05 ???????? ?????????? ... ??? p ?????????? 2 ??????????? 0 ?????????.

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???????? : ??????

??????????????? p ????? 0.07 ?. ??????? 0.05 ????????????????????????????? 2002 ? 4 ?????????? ...

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?1lLi ? ? ?????????????????

672. ?????????????????????????????. 673. ????????????????????????????. 674. ??????0.05????? 675.

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?1lLi ? ? ?????????????????

672. ?????????????????????????????. 673. ????????????????????????????. 674. ??????0.05????? 675.

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?????????????????????????????? ...

2????? TD-SCDMA ?????????????????????????????????TD-SCDMA ?. ??????????????????????????? ...

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?????0607?1?

?.T)???. ?????? p??????? 5?? ??.????. ?????????????????, ???????. ?????7?4)???????. 4.????? ...

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165. ?????????????????????????

Welch ?t??????? 2 ???? t ???????????????????????. ????????? 0.05 ??????????????? ??. ???????? ...

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???????????????????????

... P??????????TD???TD. ?????????????SNPs?GABA??? ... 0.05??????SNPs?8??? (ABAT, ALDH9A1,. GABRA3, GABRA4, GABRB2 ...

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????????????

???????????????????? 1 ?????????????? RMST ?. ????????RMST ??????????????????????????????.

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Title ????????????????????????? ??? ...

*P < 0.05?**P < 0.01?##P < 0.01??????????? 2?PGRN ? TDP-43 ???????????????????. ?????????TDP-43 ??????? ...

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