Alzheimer's Disease, Obesity, and Type 2 Diabetes - Digital CSIC
While weight loss?due to CR, intermittent fasting, or other en- ergy restriction methods?has its health benefits, fasting may impact health ... Fasting drives the metabolic, molecular and geroprotective effects of ...
Obesity and type 2 diabetes. (T2D) can lead to cognitive decline and neurodegeneration [32,33]. Insulin resistance is a key process in both ... Preventing Alzheimer's Disease and Cognitive Decline: Evidence ...
Intermittent fasting (IF) has also been demonstrated to improve neuropathological features and cognitive abnormalities in AD, where it leads ... Dietary Factors and Cognitive Health
Given that fatty acids are the essential building blocks for nearly all lipid species and excess fatty acids are associated with lipo- toxicity to both neuronal ... Interictal Spikes in Alzheimer's Disease - bioRxiv
We found that all three restricted diets improved glucose tolerance after 9 weeks on the diet (Fig. 1f) and similarly after 13 weeks on the diet (Extended Data ... Alzheimer's Disease & Neuronal Dysfunction - DTU Orbit
1997 Dietary links to Alzheimer's disease. Alzheimer's Dis Rev 2 ... tacrine and lecithin in mild to moderate Alzheimer's disease: double blind trial [see. Unraveling Molecular Mechanisms Underlying Alzheimer's disease ...
Objectives: To assess whether previous research on purported risk or protective factors for. Alzheimer's disease (AD) and cognitive decline is of sufficient ... The Journal of Prevention of Alzheimer's Disease
Furthermore, hypothalamic dysfunction can also be a driver of AD pathology. Here we offer a brief appraisal of hypothalamic dysfunction in AD ... High-fat diets and cognition: effects and mechanisms
Many observational studies and several randomized controlled trials found an association between higher omega-. 3 intake and reduced risk of cognitive decline ... The link between ceramide transporters, innate immunity and ...
Finally, a recent study of Horvath and colleagues described a 1.5 times faster decline of global cognitive performances of AD patients with EA ... A translational study of the link between Alzheimer's disease, sleep ...
hypothesis that silencing the MS cholinergic neurons selectively would reduce IIS. 70. We used mice that simulate aspects of AD: Tg2576 mice, ... State switching and high-order spatiotemporal organization of ...
(2023). Alzheimer's Disease & Neuronal Dysfunction: Brain Stimulation as a Possible. Substitute or Supplement for Medication? Technical ... Encadrant AGULHON Cendra mail cendra.agulhon@parisdescartes ...
Indeed, in the developing human brain, hyperinsulinemia and hypoglycemia are accompanied by neuronal death and excitotoxic process such as ... Masitinib AB Science - European Medicines Agency
Conclusion: Multimodal non-pharmacological interventions have the potential to complement singular therapeutic approaches by addressing multiple modifiable risk ...
