Role of the environment in establishment of definitive haematopoiesis
Unlike in humans, definitive hematopoiesis (production of adult-type blood cells) in mice primarily occurs in the bone marrow at the late stage of gestation ...
Developmental Origins of the Murine Hematopoietic SystemThe yolk sac produces primitive erythrocytes and myeloid progenitors and the AGM region produces the first multipotent progenitors and hematopoietic stem cells. Regulation of Hematopoietic Stem CellsWhile occurring primarily in the bone marrow of adult animals, hematopoiesis can occur in extramedullary sites during times of organismal stress ... Chapter 1 - UvA-DARE (Digital Academic Repository)Blood formation during fetal development primarily occurs in the liver and is generally less studied than adult blood formation, which takes place in the bone ...
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