Prise en charge médicale de la récidive du cancer épithélial de l ...

Abstract: Poly (ADP-ribose) polymerase (PARP) inhibitors (PARPi) induce cytotoxic effects as single agents in tumors characterized by defective ...







SETD1A-dependent EME1 transcription drives PARPi sensitivity in ...
PARPi have been largely adopted in triple-negative metastatic breast cancer, but their place has been less clearly defined in endocrine-receptor ...
The role of PARP in DNA repair and its therapeutic exploitation
PARPi. In malignant cells with integral DDR mechanisms,. PARPi could be used in combination with DNA-damaging agents to increase radiosensitivity ...
Role of PARP Inhibitors in Cancer Immunotherapy: Potential Friends ...
PARPi treatment which directly cleaves GSDME and, subsequently induces pyroptosis.



Autres Cours:

Combining PARP with ATR inhibition overcomes PARP inhibitor and ...