Expression of Iron-Regulatory Hormone Hepcidin ... - eScholarship
Resistance to hepcidin is conferred by hemochromatosis-asso- ciated mutations of ferroportin. ... Pettersen, E.F., Goddard, T.D., Huang, C.C., ...
Resistance of ferroportin to hepcidin binding causes pulmonary iron ...Objectives: The hepcidin?ferroportin system is involved in both conditions associated with iron-restricted erythropoiesis in renal anemia: iron deficiency ... Resistance of Ferroportin to Hepcidin Binding causes Exocrine ...Thus, the hepcidin-ferroportin axis must be tightly regulated to maintain serum iron levels. Hepcidin is a peptide of 25 amino acids and is ... Mechanism of Ca2+ transport by ferroportin - eLifeHepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science. 2004 Dec 17;306(5704):2090?3. 6.
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