Active transport of the ubiquitin ligase MID1 along the ... - SciSpace

Here, we show that ubiquitin can mediate substrate destabilization with direct consequences for proteasomal degradation. To carry out these.







Ubiquitination modulates a protein energy landscape site ... - bioRxiv
Trafficking of multiple proteins is controlled reversibly by ubiquitin and/or SUMO directly or indirectly via regulation of transport machinery components.
Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3
Lysosomal degradation of ubiquitinated TM-proteins typically involves their transport to endosomes, followed by the formation of so-called multi ...
Site-specific ubiquitination affects protein energetics ... - eScholarship
First, the ubiquitin-activating enzyme, or E1, forms a high energy thiol ester bond with ubiquitin in an ATP-dependent reaction. The next step is transfer of ...



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Ubiquitin-binding domains